Alpaca health · Other conditions

Juvenile Immunodeficiency Syndrome (JLIDS) in Alpacas

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Not usually an emergency, but it needs a diagnosis and a plan.

A rare inherited immune disorder of young camelids (mostly llamas) causing repeated infections from about 6-24 months of age.

Category
Other conditions
Urgency
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Also called
Juvenile llama immunodeficiency syndrome

Signs & symptoms

  • Recurrent infections that don't respond well to treatment
  • Poor growth
  • Death before 3 years

What causes it?

Likely inherited defect in antibody production.

Risk factors

  • Specific bloodlines

How vets diagnose it

Blood IgG levels and exclusion of other causes.

Treatment

Supportive only.

Prevention

  • Avoid repeating matings that produced affected animals

Research & references

PubMed lists 6 peer-reviewed papers on this topic in camelids. The most relevant include:

  1. Ill thrift and juvenile llama immunodeficiency syndrome. Hutchison JM, Garry F The Veterinary clinics of North America. Food animal practice, 1994. PubMed 7953965 · DOI · cited 2×
  2. Flow cytometric analysis of an immunodeficiency disorder affecting juvenile llamas. Davis WC, Heirman LR, Hamilton MJ et al. Veterinary immunology and immunopathology, 2000. PubMed 10760393 · DOI · cited 25×
  3. Immunodeficiency syndrome associated with wasting and opportunistic infection in juvenile llamas: 12 cases (1988-1990). Hutchison JM, Garry FB, Johnson LW et al. Journal of the American Veterinary Medical Association, 1992. PubMed 1429138 · cited 5×
  4. Bovine leukemia virus infection in a juvenile alpaca with multicentric lymphoma. Lee LC, Scarratt WK, Buehring GC et al. The Canadian veterinary journal = La revue veterinaire canadienne, 2012. PubMed 22942445 · cited 26×
  5. Immunodeficiency syndrome in a 3-year-old llama. Sivasankar M The Canadian veterinary journal = La revue veterinaire canadienne, 1999. PubMed 10200887
  6. Prospective characterization of the clinicopathologic and immunologic features of an immunodeficiency syndrome affecting juvenile llamas. Hutchison JM, Garry FB, Belknap EB et al. Veterinary immunology and immunopathology, 1995. PubMed 8746696 · DOI · cited 12×

Frequently asked questions

What is juvenile Immunodeficiency Syndrome (JLIDS) in alpacas?
A rare inherited immune disorder of young camelids (mostly llamas) causing repeated infections from about 6-24 months of age.
What are the signs of juvenile Immunodeficiency Syndrome (JLIDS)?
Recurrent infections that don't respond well to treatment, poor growth and death before 3 years.
How do you prevent juvenile Immunodeficiency Syndrome (JLIDS)?
Avoid repeating matings that produced affected animals.
Is juvenile Immunodeficiency Syndrome (JLIDS) an emergency?
Book a vet visit soon. Not usually an emergency, but it needs a diagnosis and a plan.

This page is educational and does not replace advice from a veterinarian who has examined your animals. Camelid medicine uses many drugs “extra-label”, so dosing must come from your vet. In an emergency, call your vet first. Read our disclaimer · How we write and review content.